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INTRODUCTION In this developed world of broad spectrum antibiotics there are less morbidity and mortality due to infectious diseases. BUT Life style diseases are making many serious challenges to healthcare authorities worldwide. From the 1940s, it became progressively more evident that lifestyle diseases were in the ascendancy. What are life style diseases? Lifestyle diseases are ailments the onset and progress of these are primarily concerned with lifestyle and behavior factors such as dietary habits, physical activities, rest, smoking, alcohol consumption, etc. Major Lifestyle Diseases Cardiovascular diseases - Ischaemic heart disease , Stroke , Peripheral arterial disease Metabolic disorders- Obesity, Hyperlipidaemia and Type 2 Diabetes Chronic respiratory diseases - Chronic obstructive pulmonary disease (COPD) and Asthma are the two main types of CRDs Cancer Other diseases associated with smoking and alcohol and drug abuse Etiology It is believed through various studies that free radicals are taking major part of the formation of lifestyle disorders. Free radicals can be formed from both, endogenous and exogenous substances due to unhealthy lifestyle. Free radicals cause lifestyle diseases such as cancer, cardiovascular diseases, arthritis, atherosclerosis, hypertension, etc. In recent years, a multitude of studies provide comprehensive evidence that increased production of reactive oxygen species are involved in the development and progression of lifestyle diseases. Characteristics of lifestyle diseases Complex etiology The onset of these diseases is insidious, they take years to develop and once encountered do not lend themselves easily to cure Multiple risk factors: There are a number of risk factors that can be divided into two primary risk sets: modifiable behavioural risk factors and non-modifiable risk factors, many of which are common for a number of diseases. Functional impairment or disability
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