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Pharmaceutical Chemistry Bloom’sTaxonomyLevels: 1.Remember 2.Understand 3. Application 4. Analysis 5.Evaluation 6. Creation Programme Name: M. Pharmacy Programme Specific Outcome (PSO) PSO 1: To prepare post-graduate students to success in technical or professional careers in various pharmaceutical industry and/ or institute and /or Health care system through excellent real time exposure to rigorous education. PSO 2: To prepare post-graduate students to learn and adapt in a globe of constantly developing trends PSO 3: To promote the development of trained human resource in Pharmaceutical Sciences for dissemination of quality education with highly professional and ethical attitude, strong communication skills, effective skills to work in a team with a multidisciplinary approach. PSO 4: To strengthen the professional and ethical attitude, effective communication skills, teamwork skills, multidisciplinary approach, and an ability to relate pharmaceutical sciences issues to broader social context. PSO 5: To provide students with a strong and well defined concepts in the fields of pharmaceutical chemistry according to the requirement of pharmaceutical industries, community and Hospital Pharmacy PSO 6: To encourage the students to participate in life-long learning process for a highly productive career and to relate the concepts of Pharmaceutical Sciences towards serving the cause of the society. PSO 7: To train the students to contribute towards health care system and counselling for prophylaxis and prevention of diseases. The Maharaja Sayajirao University of Baroda Academic Year 2019-20 Faculty of Pharmacy Modern pharmaceutical analytical techniques (MPH 101T): Regular Programme Core / Elective / Foundation Year I MPH 101T: Modern Credits / Hours per week 04 pharmaceutical analytical techniques Semester I Year of Introduction: 2000 Maximum Marks / Grade 10 Year of Syllabus Revision: 2019 0 Mode of Transaction Lectures and Tutorials Course Outcomes (CO) MQA 102T (Theory) CO1 The analysis of various drugs in single and combination dosage forms CO2 Theoretical and practical skills of the instruments Unit Topic/Uni Contact Weightage BT CO PSO Elemen Releva Relatio No. t Hours (%) Level t s of nce to n to Employ Local Gender ability (L)/ (G), (Emp)/ Nation Enviro Entrep al (N)/ n reneur Regiona mentan ship l d (Ent)/ (R)/Glo Sustain Skill b al (G) ability Develo develo (ES), p ment p Human (SD) mental Values needs (HV)an d Professi onal Ethics 1 11 18 1, 2, 3, 4 CO1 PSO4 (PE) UV-Visible spectroscopy: Introduction, Theory, Laws, Emp N PE Instrumentation associated with UV-Visible spectroscopy, SD G Choice of solvents and solvent effect and Applications of UV- Visible spectroscopy. IR spectroscopy: Theory, Modes of Molecular vibrations, Sample handling, Instrumentation of Dispersive and Fourier - Transform IR Spectrometer, Factors affecting vibrational frequencies and Applications of IR spectroscopy. Spectroflourimetry: Theory of Fluorescence, Factors affecting fluorescence, Quenchers, Instrumentation and Applications of fluorescence spectrophotometer.Flame emission spectroscopy and Atomic absorption spectroscopy: Principle, Instrumentation, Interferences and Applications. 2 NMR spectroscopy: Quantum numbers and their role in NMR, 11 18 1, 2 CO2 PSO4 Emp N PE Principle, Instrumentation, Solvent requirement in NMR, SD G Relaxation process, NMR signals in various compounds, Chemical shift, Factors influencing chemical shift, Spin-Spin coupling, Coupling constant, Nuclear magnetic double resonance, Brief outline of principles of FT-NMR and 13C NMR. Applications of NMR spectroscopy. 3 Mass Spectroscopy: Principle, Theory, Instrumentation of 11 18 1,2 CO2 PSO4 Mass Spectroscopy, Different types of ionization like electron Emp N impact, chemical, field, FAB and MALDI, APCI, ESI, APPI SD G PE Analyzers of Quadrupole and Time of Flight, Mass fragmentation and its rules, Meta stable ions, Isotopic peaks and Applications of Mass spectroscopy 4 Chromatography: Principle, apparatus, instrumentation, 11 18 1, 2 CO2 PS chromatographic parameters, factors affecting resolution and O4 Emp N applications of the following: SD G PE a) Paper chromatography b) Thin Layer chromatography c) Ion exchange chromatography d) Column chromatography e) Gas chromatography f) High Performance Liquid chromatography g) Affinity chromatography 5 Electrophoresis: Principle, Instrumentation, Working 11 18 1,2 CO2 conditions, factors affecting separation and applications of the PS Emp following: O4 SD N PE G
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