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PHARMACY PRACTICE M. Pharm SEMESTER-I Course Code Course Name Credits PP-510 Pharmacy Practice-I 1 PP-520 Clinical and Applied Therapeutics-I 3 PP-530 Clinical Pharmacy 1 PE-520 Biopharmaceutics and Pharmacokinetics 2 GE-510 Biostatistics 2 GE-511 Seminar / Presentation 1 LG-511 Clinical Placement 4 LG-512 Computer Applications 2 Total Credit 16 SEMESTER-II Course Code Course Name Credits PP-610 Pharmacy Practice-II 1 PP-611 Pharmacy Practice-III (Community and Rural Pharmacy) 1 PP-620 Clinical and Applied Therapeutics-II 3 PP-630 Evidence Based Medicine and Critical Appraisal 2 PP-631 Clinical Biostatistics 1 GE-611 Seminar / Presentation 1 LG-611 Clinical Placement 5 Total Credit 14 SEMESTER-III [Project (22 weeks)] Course Code Course Name Credits TH-598 Synopsis 5 TH-599 Presentation 3 Total Credit 8 SEMESTER-IV Course Code Course Name Credits TH-698 Thesis 9 TH-699 Defence of Thesis 3 Total Credit 12 Grand Total (I to IV semesters): 50 NIPER-Guwahati, Nits Mirza Rd, Mirza, Parlli Part, Assam 781125 Pharmacy Practice SEMESTER-I PP-510 Pharmacy Practice-I (1 credit) 1. Understanding terminologies and concepts: Primary, secondary and tertiary care; Pharmacy Practice; Institutional, hospital, ward clinical and community pharmacy; Patient confidentiality, patient compliance, counseling, informed consent. 2. Pharmaceutical care and planning 3. Hospital pharmacy: Overview of organization and structure (comparison with community pharmacy), basic hospital pharmacy services. 4. Specialized services e.g. Drug Information Centre and service provision. 5. Role of patients in decision-making regarding therapeutic management: Factors affecting patients’ decision to take/not to take the medication. 6. Professional Responsibilities: Profession of pharmacy and pharmacists as practitioners; Responsibilities of pharmacy practitioners as stated in developed countries; Relevance and scope of adopting these in India; Opportunities and legislation; Relationship with other health care professionals-doctors, nurses, paramedical staff, drug inspectors, excise officers and police officers; Ethics of practice. 7. Skills: Communication, counseling; Reading, writing, thinking; Factors affecting development of these skills. Recommended books: 1. A Practical Guide to Contemporary Pharmacy Practice by Judith E. Thomson, Lippincott Williams & Wilkins 2. Introduction to Hospital and Health-System Pharmacy Practice by David A. Holdford and Thomas R. Brown 3. Communication Skills in Pharmacy Practice : A Practical Guide for Students and Practitioners, by Robert S. Beardsley, Carole Kimberlin and William N. Tindall 4. Hospital Pharmacy by Martin Stephens 5. Hospital Pharmacy, by Willium Hassan, Lea &Febiger NIPER-Guwahati, Nits Mirza Rd, Mirza, Parlli Part, Assam 781125 PP-520 Clinical and Applied Therapeutics-I (3 credits) 1. Geriatrics: Issues based on age related physiologic and pharmacokinetic/dynamic changes; Variations in management from other patient groups; Pharmaceutical care plan in view of compliance, ability to use devices for other diseases/disorders) including discharge and home care plan. 2. Paediatrics: Specific childhood diseases and management; Immunizations, national immunization programmes and scope for pharmacists’ involvement in these; Special issues of paediatric management; Dosage adjustments based on age and physiological and pharmacokinetic/dynamic development stage; Availability of ‘adequate’ formulations, dosage forms; Drug administration, timing: Compliance, psychology and hormonal changes in adolescents. 3. Cardiology: Hypertension; Congestive heart failure 4. Cardiology: Angina; Myocardial Infection; Arrhythmias; Lipid disorders; Guidelines for management of patient and monitoring drug therapy, TDM for digoxin. 5. Respiratory diseases and treatment: Asthma; COPD; TDM of Theophyllin; Use and maintenance of different inhalers and devices, operation of oxygen cylinders; Monitoring therapy; Guidelines ; Respiratory infections (treatment in view of resistant states, isolation, monitoring therapy and duration of treatment , side effects, drug interactions)-URTIs and LRTIs; TB, pneumonia. 6. Nephrology: Influence and important of fluid and electrolyte balance and acid-base balance; Acute renal failure; Chronic renal failure; Renal dialysis (types and points of pharmacists’ involvement). 7. Infections and antimicrobial therapy: Special emphasis on communicable diseases in India, introduction to related national health programmes; UTIs, GI, CNS, bone and joint infections, sexually transmitted diseases, mycotic parasitic infections; Need and relevance of antibiotic polices. 8. Diabetes: Type 1 and 2 (incidence, prevalence, etiology, influencing factors, genetic basis); Treatment option and guidelines; Insulin types and formulations, administration monitoring therapy, patient education; Resistant cases (causes, alternatives to treatment); Management of gestational diabetes. Note: Applicable to all practice based subjects/topics a) Teaching of individual drugs should not be included: Only specific practical as against theoretical issues of drugs commonly used in practice should be discussed along with the recent advances in drugs, formulations and dosage forms. NIPER-Guwahati, Nits Mirza Rd, Mirza, Parlli Part, Assam 781125 b) Teaching should be practice and primary literature based with emphasis on issues in therapy, advances and guidelines with case studies throughout the course. c) In all areas, primary literature review and individual appraisal (as can be assessed in practice) of recent developments is encouraged. Recommended books: 1. Koda-Kimble and Young’s Applied Therapeutics: The Clinical use of Drugs by Brian K. Alldredge, Robin L. Corelli, Michael E. Ernst, and B. Joseph Guglielmo 2. Pharmacotherapy: A Pathophysiologic Approach by Joseph DiPiro, Robert L. Talbert, Gary Yee and Gary Matzke 3. Clinical Pharmacy and Therapeutics by Eric T. Herfindal and Joseph L. Hirschman Clinical Pharmacy and Therapeutics, by Robert Walker and Cate Whittlesea 4. Goodman and Gillman’s Manual of Pharmacology and Therapeutics by Laurence Brunton, Donald Blumenthal, lain Buxton and Keith Parker 5. Goodman and Gillman’s The Pharmacological Basis of Therapeutics, by Laurence Brunton, Bruce Chabner and Bjorn Knollman PP-530 Clinical Pharmacy (1 credit) 1. Evolution of Clinical Pharmacy and current scenario (ward and clinical pharmacy services responding to symptoms) 2. Modified release doses forms: Advantagesand limitations of modified release dosage forms for patient treatment. 3. Update on advances in biotechnology and gene therapy 4. Biochemical and other laboratory data interpretation (in association with clinical information and limitations of laboratory results): Case studies (Workshops) of renal, hepatic, cardiac, respiratory, diabetic (including dose adjustment of insulin with glucose monitoring), epileptic (including DIs, TDM) and elderly osteoporotic patients; Inclusion of issues around hypo/hyperthyroid/thyrotoxicosis and anticoagulation therapy within these cases. 5. Therapeutic drug monitoring of digoxin, theophylline, phenytoin phenobarbitone, carbamazepine and gentamicin 6. Understanding audit: Auditcycle, identifyingkey issues, setting standards; Audit process; Results and re-audit 7. Clinical trials and pharmacists’ involvement: Legal and ethical requirements of trials 8. Research Methods: Designing, planning and carrying out a research project; Research methodologies (quantitative, qualitative) – uses, adequacy and limitations; Choice of NIPER-Guwahati, Nits Mirza Rd, Mirza, Parlli Part, Assam 781125
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