122x Filetype PDF File size 0.61 MB Source: www.hanmipharm.com
ASPEN 2021 Nutrition Science & Practice Conference Intestinotrophic effect of a novel long-acting GLP-2 analog, HM15912, in animal model for short bowel syndrome and potential as monthly administration Jae Hyuk Choi, JinBong Lee, EunJinPark, Sung Min Bae, DaeJinKim, Young HoonKim, In Young Choi Sr. manager / Bio Discovery Team HanmiPharm. Co., Ltd., Seoul, Republic of Korea Disclosures Employee of Hanmi Pharm. Co., Ltd. ed. All Rights Reserv ition. Nutr Enteral and r Parenteral fo merican Society A | ASPEN © 2021 What GLP-2 is Proglucagon 33 amino acids Various biological actions Glicentin GLP-1 IP2 GLP-2 ↓ Food intake GRPP OXM ed. ↓ Bone resorption All Rights Reserv ↓ Gastric motility & ition. secretion Nutr Enteral and Intestinal L cell ↑ Energy absorption & mucosal morphology r Parenteral - Intestinal growth fo - Mucosal integrity merican Society A | ASPEN © 2021 What GLP-2 is Proglucagon 33 amino acids Various biological actions Glicentin GLP-1 IP2 GLP-2 ↓ Food intake GRPP OXM ed. ↓ Bone resorption All Rights Reserv ↓ Gastric motility & ition. “Crypt cell proliferation via GLP-2/IGF-1 axis” secretion Nutr Enteral and Intestinal L cell ↑ Energy absorption & mucosal morphology r Parenteral - Intestinal growth fo - Mucosal integrity merican Society A | ASPEN © 2021
no reviews yet
Please Login to review.