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Emergency Medicine Practice Clinical Pathways: Evidence To Improve Patient Care In Emergency Medicine BROUGHT TO YOU EXCLUSIVELY BY THE PUBLISHER OF: Emergency Medicine Practice Pediatric Emergency Medicine Practice EM Practice Gideine Udate Te Lie ng Learning and Seement Stdy Gide EM Critica Care E Oercr ding S ti n Table Of Contents General Emergency Medicine Clinical Pathway For Evaluation Of Patients With Suspected Acute Hepatic Injury ..........1 Clinical Pathway For Asymptomatic Hypertension ........................................................................ 2 Clinical Pathway For Symptomatic Hypertension ........................................................................... 3 Clinical Pathway For Treatment Of Skin And Soft Tissue Infections ........................................4 Clinical Pathway For The Management Of The Postpartum Patient With Headache .......5 Clinical Pathway For The Management Of The Postpartum Patient With Elevated Blood Pressure (> 140 Systolic Or > 90 Diastolic) .......................................................................... 6 HEENT Emergencies Clinical Pathway For Blunt Eye Trauma ............................................................................................... 7 Clinical Pathway For Penetrating Eye Trauma .................................................................................. 8 Clinical Pathway For Treatment Of Acute Otitis Media ................................................................ 9 Hematologic Emergencies Clinical Pathway For Evaluation Of Suspected Malignant Epidural Spinal Cord Compresion .................................................................................................................................................10 Clinical Pathway For The Management Of Hypercalcemia Of Malignancy ........................11 Clinical Pathway For Management Of Tumor Lysis Syndrome ................................................12 Clinical Pathway For The Initial Management Of Neutropenic Fever ...................................13 Toxicologic Emergencies Clinical Pathway For Single APAP Ingestion ...................................................................................14 Clinical Pathway For Initial Evaluation Of Toxic Alcohol Poisoning .......................................15 Clinical Pathway For Management Of Methanol And Ethylene Glycol Poisoning ...........16 Clinical Pathway For Management Of Isopropanol Poisoning ................................................16 Full issue available free for subscribers or for purchase for non-subscribers on our website. Full subscriptions are also available. i We’d love your feedback on this iPad download — please share your comments and questions in this survey. Return to the Table of Contents. Clinical Pathway For Evaluation Of Patients With Suspected Acute Hepatic Injury AST and/or ALT > 300 U/L? YES NO AST > 3000 U/L? AST > 2x ALT? YES NO YES NO Probable toxic or ischemic ALK < 3x Upper NI? History of ethanol abuse? Not acute hepatic injury injury YES NO YES NO Acute hepatitis panel History of drug exposure? Alcoholic hepatitis POSITIVE NEGATIVE YES NO IgM anti-HAV Probable drug injury HCV exposure? NO POSITIVE NEGATIVE YES Acute HAV IgM NEGATIVE Anti-HCV HCV RNA Consider obstruction, anti-HBc other causes POSITIVE POSITIVE POSITIVE NEGATIVE Acute HBV Previous neg? YES NO Acute HCV Possible acute HCV Abbreviations: ALK, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HAV, hepatitis A virus; HBc, hepatitis B core antigen; HBV, hepatitis B virus; HCV, hepatitis C virus; IgM, immunoglobulin M antibody; NI, normal. CLINICAL CHEMISTRY. ONLINE by Dufour, Lott, Nolte, Gretch, Koff, Seef. Copyright 2000 by AMERICAN ASSOCIATION FOR CLINICAL CHEMIS- TRY, INC. Reproduced with permission of AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, INC in the format Journal via Copyright Clear- ance Center. Emergency Medicine Practice © 2010 10 EBMedicine.net • April 2010 Full issue available free for subscribers or for purchase for non-subscribers on our website. Full subscriptions are also available. We’d love your feedback on this iPad download — please share your comments and questions in this survey. Return to the Table of Contents. 1 Clinical Pathway For Asymptomatic Hypertension Vital signs show BP elevation Recheck BP BP normal now? YES Home; recheck BP in 1 month (Class III) NO BP > 180/110 mm Hg? Home; recheck BP in NO 1 week to 1 month YES (Class III) HYPERTENSIVE URGENCY Consider ancillary testing: CBC BMP Chest x-ray ECG Signs of end-organ NO Contact primary care damage? provider; follow up 1 day to 1 week YES Consider starting 2-drug oral therapy, especially if BP > 200/120 mm Hg Go to the Clinical Pathway Do NOT attempt to nor- For Symptomatic Hyper- malize BP in the ED tension, next page (Class III) Abbreviations: BMP, basic metabolic panel; BP, blood pressure; CBC, complete blood count; ECG, electrocardiogram; ED, emergency department. Class Of Evidence Definitions Each action in the clinical pathways section of Emergency Medicine Practice receives a score based on the following definitions. Class I Class II Class III Indeterminate tatives from the resuscitation • Always acceptable, safe • Safe, acceptable • May be acceptable • Continuing area of research councils of ILCOR: How to De- • Definitely useful • Probably useful • Possibly useful • No recommendations until velop Evidence-Based Guidelines • Proven in both efficacy and Level of Evidence: • Considered optional or alterna- further research for Emergency Cardiac Care: effectiveness • Generally higher levels of tive treatments Level of Evidence: Quality of Evidence and Classes Level of Evidence: evidence Level of Evidence: • Evidence not available of Recommendations; also: • One or more large prospective • Non-randomized or retrospec- • Generally lower or intermediate • Higher studies in progress Anonymous. Guidelines for car- studies are present (with rare tive studies: historic, cohort, or levels of evidence • Results inconsistent, contradic- diopulmonary resuscitation and exceptions) case control studies • Case series, animal studies, tory emergency cardiac care. Emer- • High-quality meta-analyses • Less robust RCTs consensus panels • Results not compelling gency Cardiac Care Committee • Study results consistently posi- • Results consistently positive • Occasionally positive results and Subcommittees, American tive and compelling Significantly modified from: The Heart Association. Part IX. Ensur- Emergency Cardiovascular Care ing effectiveness of community- Committees of the American wide emergency cardiac care. Heart Association and represen- JAMA. 1992;268(16):2289-2295. This clinical pathway is intended to supplement, rather than substitute for, professional judgment and may be changed depending upon a patient’s individual needs. Failure to comply with this pathway does not represent a breach of the standard of care. Copyright © 2010 EB Practice, LLC d.b.a. EB Medicine. 1-800-249-5770. No part of this publication may be reproduced in any format without written consent of EB Practice, LLC d.b.a. EB Medicine. Emergency Medicine Practice © 2010 14 EBMedicine.net • June 2010 Full issue available free for subscribers or for purchase for non-subscribers on our website. Full subscriptions are also available. We’d love your feedback on this iPad download — please share your comments and questions in this survey. Return to the Table of Contents. 2
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